Re: 100% CPU with NONMEM

From: mark.e.sale@gsk.com Subject: Re: [NMusers] 100% CPU with NONMEM Date: Wed, 01 Feb 2006 Sam, Sorry to disagree, but HT does not work for NONMEM. The multiple instruction paths on the Intel chips include only one for floating point operations, and 4 for integer operations. We have benchmarked NONMEM with and without HT, and it makes no difference, and makes no difference in responsiveness of the GUI. HT is basically intended for gamers Mark Sale M.D. Global Director, Research Modeling and Simulation GlaxoSmithKline 919-483-1808 Mobile 919-522-6668