ka and Duration

From: Mahesh Samtani Date: January 07, 2006 technical Source: cognigencorp.com
From: "Samtani, Mahesh [PRDUS]" MSamtani@prdus.jnj.com Subject: [NMusers] ka and Duration Date: Sat, 7 Jan 2006 15:45:27 -0500 Hello, Is it possible to specify the duration of a first order input and fit ka in NONMEM without using DEQs and IF/THEN statements? We are trying to model the PK of a drug with simple 2-compartment disposition. The drug is delivered by a formulation that is applied for 7 days and delivers drug by first order input. Kindly advise, Mahesh ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Mahesh N. Samtani, Ph.D. Scientist, Advanced PK-PD Modeling & Simulation Clinical Pharmacology and Experimental Medicine Johnson & Johnson Pharmaceutical R&D PRD 2723, Raritan, NJ 08869 PH # (908) 704-5367 Email: msamtani@prdus.jnj.com ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

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Jan 07, 2006 Mahesh Samtani ka and Duration
Jan 07, 2006 Marc Gastonguay Re: ka and Duration
Jan 07, 2006 Malaz Abutarif RE: ka and Duration
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