Re: faster PC to run nmv

From: mark.e.sale@gsk.com Subject: Re: [NMusers] faster PC to run nmv Date: Mon, 15 Aug 2005 12:14:59 -0400 Sam, NONMEM is virtually all double precision floating point calculations. While the buffers in NONMEM are set to be pretty small (extremely small by today standards), disc I/O is essentially a non issue, as modern operating systems will provide the buffering that makes disc I/O irrelevant. That makes selecting a machine/CPU pretty easy compared to more modern applications with some of this new fangled stuff like pictures - sometimes even moving pictures. AMD chips are really optimized for games/graphics, not number crunching. (deeper instruction path for speculative execution for anyone interested). Basically, NONMEM performance is very well correlated with floating point benchmarks, which can be found at: http://www.spec.org/cpu2000/results/cpu2000.html - look for CFP2000 Bottom line: Dell Precision Workstation 3.8 Ghz Pentium 4. Mark Sale M.D. Global Director, Research Modeling and Simulation GlaxoSmithKline 919-483-1808 Mobile 919-522-6668 _______________________________________________________