RE: log transformed data and multi compartment PK

From: David Dai david.dai@bms.com Subject: RE: [NMusers] log transformed data and multi compartment PK Date: Tue, 26 Jul 2005 18:05:20 -0400 Hi, Immo: Log transformation is a better way to fit parent/metabolite simultaneously. I never got converged with FOCE-interaction using real DV data. but quite happy with log transformed data and run time was much shorter. In your error block, you might want to add the following lines to avoid the error messages: CALLFL=0 IPRED = -6 IF (F.GT.0) IPRED =LOG(F) Additionally, have you tried a different error structure for log-transformed data such as combined additive and proportional model? Best, david