RE: problem with acquiring post hoc estimates

From: Leonid Gibiansky lgibiansky@emmes.com Subject: RE: [NMusers] problem with acquiring post hoc estimates Date: Tue, May 18, 2004 12:01 pm Kristel Few questions: It would help to see a full control stream, not only the PK block. What is VF ? Why CL1 depends on frequency of administration (THETA(6)**FREQ) ? How Cmin is defined? Why oral dose is modeled as zero-order bolus dose (infusion with duration D1) rather than via absorption KA? I am not 100% sure but I would use EVID=1 rather than EVID=4 at the first line of your data set. Thanks Leonid