NONMEM Tips #18 - Oct 22, 2003 - Alison's nmsee5 for summarizing NONMEM output
From: "Bachman, William" bachmanw@globomax.com
Subject: [NMusers] NONMEM Tips #18 - Oct 22, 2003 - Alison's nmsee5 for summarizing NONMEM output
Date: 10/22/2003 1:25 PM
This tip is to remind users of a free utility written by Alison Boeckmann
for summarizing NONMEM output. The code for this utility, nmsee5.for, and
instructions are available at:
ftp://ftp.globomaxnm.com/Public/nonmem/nmsee/
To use the utility, compile the fortran code to create the executable
nmsee5.exe, e.g.:
c:\nmv\run> df nmsee5.for
Then redirect the result file of a NONMEM or PDx-Pop run to the nmsee5.exe
program:
c:\nmv\run> nmsee5 < 101.res
The output will be sent to the console and look something like this:
PROBLEM NO. 1
aspirin 1CMT model w. lag
INITIAL ESTIMATE OF THETA:
9.00E+01 6.00E+02 4.60E+00 2.30E-01
LOWER BOUND ON THETA:
0.00E+00 0.00E+00 0.00E+00 0.00E+00
UPPER BOUND ON THETA:
1.00E+06 1.00E+06 1.00E+06 1.00E+06
INITIAL ESTIMATE OF OMEGA:
1.50E-01
0.00E+00 2.60E-01
INITIAL GRADIENT:
-2.04E+03 -1.15E+02 1.83E+02 -3.30E+02 -3.12E+02 -1.52E+01
FINAL GRADIENT:
1.57E-02 -1.14E-01 -1.44E-01 8.63E-01 3.77E-02 -1.10E-02
FINAL PARAMETER:
1.20E-01 1.06E-01 7.36E-02 1.11E-01 1.19E-01 -7.68E-06
MINIMIZATION SUCCESSFUL
NO. OF FUNCTION EVALUATIONS USED: 139
NO. OF SIG. DIGITS IN FINAL EST.: 4.0
MINIMUM VALUE OF OBJECTIVE FUNCTION
109.784
FINAL PARAMETER ESTIMATE
THETA - VECTOR OF FIXED EFFECTS
1.29E+02 6.74E+02 2.49E+00 2.82E-01
OMEGA - COV MATRIX FOR RANDOM EFFECTS - ETAS
2.14E-01
0.00E+00 1.53E-09
The output of nmsee5.exe can also be saved to a file as follows:
c:\nmv\run> nmsee5 < 101.res > 101.sum
A variety of command line options are available for use with nmsee5 and are
described in the directions.
(This tip is supplied "gratis" and without implicit or explicit support from
GloboMax LLC).
Previous tips may be found in the NONMEM Repository@GloboMax:
ftp://ftp.globomaxnm.com/Public/nonmem/tips/
See the index.txt file for a listing of previous tips.
***************************************************************************
If you have a "tip" or a better way to do things, by all means, feel free to
post them! One of the reasons for doing this (other than good PR for
GloboMax), is to stimulate discussion. We at GloboMax can learn from your
experience as well. Do you have a "tip" you would like to share, but would
prefer to remain anonymous? If so, you may forward it to us and your
identity will be withheld. Distribution as a "Tip of the Week" will be at
the discretion of nmconsult@globomaxnm.com.
***************************************************************************
nmconsult@globomaxnm.com
GloboMax
The Strategic Pharmaceutical Development Division of ICON plc
7250 Parkway Drive, Suite 430
Hanover, MD 21076
Voice: (410) 782-2205
FAX: (410) 712-0737
_______________________________________________________