RE: Parameter %RSE vs ETA %RSE

From: Sam Liao <sliao@pharmaxresearch.com> Subject: RE: [NMusers] Parameter %RSE vs ETA %RSE Date: 7/17/2003 3:50 PM Hi Daniel: Based on CL and V estimates, the elimination half-life is 0.85 hr while the absorption half-life is 3.5 hours. How is this compared with those half-lives obtained from intensive PK sampling? If there is a flip-flop, V estimate will be affected too. It may be a good ideal to fix KA to avoid flip-flop, if the sparse data do not have enough data in the absorption phase. Best regards, Sam Liao _______________________________________________________