simulated negative concentration

From:Yaning Wang Subject:[NMusers] simulated negative concentration Date:Thu, 13 Feb 2003 19:17:49 -0500 Dear NM users: How can I prevent from simulating negative concentrations? My error model is Y=F(1+EPS(1))+EPS(2). How can I make sure that NONMEM will only simulate positive concentrations or, even more strictly, within an interval? An example will be highly appreciated. Thanks Yaning Wang Department of Pharmaceutics College of Pharmacy University of Florida