Re: NONMEM runtimes

From: Dirk.Zeumer@bc.boehringer-ingelheim.com Subject: Re: [NMusers] NONMEM runtimes Date: Mon, 29 Apr 2002 15:17:46 +0200 Dear all, I don't think that disk I/O is the main problem here. As far as I understand the hardware used for the (final) tests with Linux and Windows was (nearly?) the same - so it seems like a compiler problem - especially by mentioning "most agressive optimization". All newer Windows compilers are able to optimize the executable for newer CPUs (as PIV or Athlon XP) which use the "Streaming SIMD Extension 2 (SSE2)". These optimization results in a significant decrease in the runtime (especially compared to the SSE version of a PIII). Correct me if I'm wrong: I assume that with Linux the range of "standard" f77 / g77 compilers were used for the tests - with no support for SSE2 (sometimes even no SSE support). Therefore I would suggest to do some tests with the Intel Fortran Compiler 6.0 wich is available also for Linux. The options available in this versions will (surprisingly) work also on AMD CPUs. By the way: it would be really nice to see some data of the test Regards, Dirk Zeumer