censored data
From: Lewis B Sheiner
Subject: censored data
Date:Sun, 13 Jan 2002 10:51:55 -0800
Here are three papers that are relevant ... All use one or more methods to deal with
censoring, although in none of the papers except #1 is that the primary focus.
1. Beal, S.L., Ways to fit a pharmacokinetic model with some data below the
quantification limit. Journal of Pharmacokinetics and Biopharmaceutics, 2001.
28(5): p. 481-504.
2. Luks, A.M., et al., Opioid-induced analgesia in neonatal dogs: pharmacodynamic
differences between morphine and fentanyl. Journal of Pharmacology and Expertimental
Therapeutics, 1998. 284: p. 136-141.
3. Lu, J., et al., Selecting reliable pharmacokinetic data for explanatory
analyses of clinical trials in the presence of noncompliance. Journal of
Pharmacokinetics and Pharmacodynamics, 2001. 28(4): p. 343-362.
--
_/ _/ _/_/ _/_/_/ _/_/_/ Lewis B Sheiner, MD (lewis@c255.ucsf.edu)
_/ _/ _/ _/_ _/_/ Professor: Lab. Med., Biophmct. Sci., Med.
_/ _/ _/ _/ _/ Box 0626, UCSF, SF, CA, 94143-0626
_/_/ _/_/ _/_/_/ _/ 415-476-1965 (v), 415-476-2796 (fax)