Bayesian fits

From: Ruediger Port Date: November 07, 2001 technical Source: cognigencorp.com
From: Ruediger Port <rep@hsc.usc.edu> Subject: [NMusers] Bayesian fits Date: Wed, 7 Nov 2001 08:45:05 -0800 (PST) Hi Paul: In case you didn't get a complete answer: Here is another example of a control file that gets individual Bayesian parameter estimates without re-estimating the population parameters: ---------------------------- $PROBLEM individual Bayesian parameter estimates $INPUT ID DV $DATA newdata IGNORE=# $SUBROUTINES $PRED Pi = THETA(1) + ETA(1) Y = Pi + EPS(1) ; a simple model ; Population parameters from the literature: $THETA 20 $OMEGA 6 $SIGMA 36 $ESTIM MAXEVALS=0 POSTHOC $TABLE ID Pi NOPRINT ONEHEADER FILE=tablefile I wouldn't do any weighting of data from parsimonious sampling because the Bayesian fit already implies that the fewer the the individual data are the less their impact is on the estimated individual parameters. ------------------------------ Good luck! Ruedi ------------------------------- Dr. R.E. Port, German Cancer Research Center, D-0200 P.O. Box 10 19 49, D-69009 Heidelberg, Germany phone: +49-6221 42-3385 fax: -3382 e-mail: r.port@dkfz.de
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Nov 05, 2001 Pierre Maitre Re: Bayesian fits
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Nov 07, 2001 Jill Fiedler-Kelly Re: Bayesian fits - NONMEM UsersNet Archive