RE: DRUG AND METABOLITE

From: Ekaterina Gibiansky Date: May 29, 2001 technical Source: cognigencorp.com
From: "Gibiansky, Ekaterina" <gibianskye@globomax.com> Subject: RE: DRUG AND METABOLITE Date: Tue, 29 May 2001 08:19:12 -0400 Atul, you have an inconsistency in your differential equations: the term -k13*A(1) should appear in the equation for the central compartment. Scaling parameter S3 should not be 1, since you measure metabolite concentrations. Also, for the linear system like yours you do not need to use $DES, you can use general linear ADVAN (ADVAN5 or ADVAN7). Katya ------------------------ Ekaterina Gibiansky, PhD Senior Scientist GloboMax LLC 7250 Parkway Drive, Suite 430 Hanover, MD 21076 Voice (410) 782-2234 FAX (410) 712-0737 E-mail: gibianskye@globomax.com

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May 28, 2001 Atul Bhattaram Venkatesh DRUG AND METABOLITE
May 29, 2001 Ekaterina Gibiansky RE: DRUG AND METABOLITE
May 29, 2001 Juan Jose Perez Ruixo RE: DRUG AND METABOLITE
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