Increasing the umber of sub-population in a mixture model

From: "HUTMACHER, MATTHEW [Non-Pharmacia/1825]" <matthew.hutmacher@pharmacia.com> Subject: Increasing the umber of sub-population in a mixture model Date: Fri, 25 May 2001 13:07:28 -0500 Hello, I have a very complicated data pattern. Many of you have given great advice on how to use a mixture model at the IOV stage and I appreciate it. I have found, that I need more sub-populations to characterize the lag-time distribution in my model (the distribution of me predicted etas are still very skewed). I have tried to increase the number of sub-populations and I get this error message: AN ERROR WAS FOUND IN THE CONTROL STATEMENTS. AN ERROR WAS FOUND ON LINE 43 AT THE APPROXIMATE POSITION NOTED: P(5)=THETA(.) X THE CHARACTERS IN ERROR ARE: 5 332 $MIX: NSPOP AND INDICES I OF P(I) MAY ONLY BE 1, 2, 3, OR 4. STOP 4 statement executed Is there a way to increase the number of allowable sub-populations. I have extended the code Dr Sheiner supplied to me for two sub-populations (at IOV level) to three: $MIX P(1)=THETA(.) P(2)=1.-THETA(.) P(3)=THETA(.) P(4)=1.-THETA(.) P(5)=THETA(.) P(6)=1.-THETA(.) NSPOP=6 Any help in this would be appreciated. Thanks again. Matt