An approach for imputing missing independent variable (covariate)

From: "Piotrovskij, Vladimir [JanBe]" <VPIOTROV@janbe.jnj.com> Subject: An approach for imputing missing independent variable (covariate) Date: Wed, 20 Sep 2000 15:10:22 +0200 Dear Colleagues, The recent discussion regarding missing covariate values was stimulating, and catalized my thinking on how to solve the problem without assuming any explicit model for a covariate. I did some simulation/fitting exercises, and the results you may find attached. Any comments are appreciated. Best regards, Vladimir ---------------------------------------------------------------------- Vladimir Piotrovsky, Ph.D. Janssen Research Foundation Clinical Pharmacokinetics (ext. 5463) B-2340 Beerse Belgium Email: vpiotrov@janbe.jnj.com An approach for imputation of missing independent variable.doc