NONMEM Analysis Strategy
From: NIclas Jonsson <niclas.jonsson@biof.uu.se>
Date: Thu, 23 Sep 1999 08:53:53 +0100 (IST)
Subject: NONMEM Analysis Strategy
One of the papers by EN Jonsson and MO Karlsson that Lewis talks about is "Automated covariate model building within NONMEM" (PharmRes 15(9) 1998, pp. 1463-1468). It describes a method with which the covariate model can be built with as much automation as possible (basically forward inclusion and backwards elimination for both liear and non-linear covariate relationships).
The procedure (written in perl) for doing this is available by anonymous ftp from ftp.biof.uu.se/pub/biof/PsN/ in the files psn0.071.tar.gz and psn07.zip depending on you plattform.
Best regards,
Niclas Jonsson