2 recent questions

From: ABoeckmann <alison@c255.ucsf.edu> Subject: 2 recent questions Date: Tue, 3 Nov 1998 10:02:36 -0800 (PST) Here are comments on two recent questions that were sent to nmusers. From: TRANCHAND Brigitte <tranchan@lyon.fnclcc.fr> Subject: initial OMEGA Brigitte needs to supply more detail. E.g., in her first run, does she supply good initial estimates of theta, or is she letting NONMEM compute the initial estimates of theta? Does her second run involve much better estimates of theta as well as omega? Or does she work with certain kinds of model or data sets? From: "Ralph Quadflieg" <quadflieg@uni-bonn.de> Subject: stepwise zero order input Ralph's difficulty turned out to be a mistake in the use of the CMT and PCMT data items.