Weighted residuals calculation

From: Bruce Charles Date: July 30, 1997 technical Source: cognigencorp.com
From: "Bruce" <bruce@uqpharmacy.pharmacy.uq.edu.au> Subject: Weighted residuals calculation Date: 29 Jul 1997 22:12:17 -0400 Fellow Users: Can anyone assist with a lucid and meaningful explanation of how weighted residuals are calculated in NONMEM? Despite what is written in Users Guide I pages 27, 29, 37, 41 (including the formulae) I still have difficulties precisely understanding the calculation outlined there. An explanation unencumbered with linear algebra jargon would be greatly appreciated. Best wishes BC + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Bruce CHARLES, PhD School of Pharmacy The University of Queensland Brisbane, Qld, Australia 4072 Telephone: +61 7 336 53194 Facsimile: +61 7 336 51688 Email: Bruce.Charles@pharmacy.uq.edu.au + + + + + + + + + + + + + + + + + + + + + + + + + + + + +