Multiple Data Sets
One can set up a multi-problem run in NONMEM, with multiple data sets.
The control file looks something like the following:
$PROBLEM title for first problem
$DATA name of first data set
$SUBROUTINES ... (or $PRED)
$PK
$ERROR
$THETA, $OMEGA $SIGMA
task specification records, eg., $ESTIM, $COV, $TABLE, $SCAT
$PROBLEM title for second problem
$DATA name of second data set
$THETA, $OMEGA $SIGMA
task specification records, eg., $ESTIM, $COV, $TABLE, $SCAT
$PROBLEM title for third problem
$DATA name of third data set
$THETA, $OMEGA $SIGMA
task specification records, eg., $ESTIM, $COV, $TABLE, $SCAT
... etc ...
Note that $SUBROUTINES/$PK/$ERROR (or $PRED) cannot appear
in subsequent problems.