Prediction Curve

Hi. We are running NONMEM on HP-UX 9.03 for a long period. Using a nonlinear model (ADVAN8 including linear and nonlinear elimination processes and different terms for inter occasional variabilities), I had the wish to make predictions on all non measured time points. Sometimes it is working using these additional records: EVID=0, PCMT=CMT=2, CONC=DV=0, and MDV=1 or EVID=2, PCMT=CMT=2, CONC=DV=0, and MDV=1 and a MSFI-file which is the result of a prior succesfully finished run without these add. records and a MSFO-file. But in most cases NONMEM crashes with the following *** FORTRAN I/O ERROR 933: END (OR BEGIN) OF FILE WITH NO "END=" SPECIFIER FILE: FILE19, UNIT: 19 LAST FORMAT: (34(1X,1P,E11.4)) ( 0) 0x80fbb06c io_ded + 0x31c [/usr/lib/pa1.1/libcl.sl] ( 1) 0x80fbea9c read_seq_unform + 0x1c8 [/usr/lib/pa1.1/libcl.sl] ( 2) 0x80fbec68 new_rc + 0x90 [/usr/lib/pa1.1/libcl.sl] ( 3) 0x80fcf9cc FTN_S_RSUE + 0x158 [/usr/lib/pa1.1/libcl.sl] ( 4) 0x0001f984 dat6 + 0x5d4 [./nmd.27205] ( 5) 0x00039bd8 outpt + 0x25e8 [./nmd.27205] ( 6) 0x00013fc4 final + 0x494 [./nmd.27205] ( 7) 0x000102b4 nonmem + 0x22c [./nmd.27205] and in the output 0PRED EXIT CODE = 1 0INDIVIDUAL NO. 1 ID= .11200000E+03 (WITHIN-INDIVIDUAL) DATA REC NO. 91 THETA= 2.83E+00 5.17E+00 8.87E+00 2.54E+01 9.48E-01 3.39E+00 5.70E-01 5.80E-03 1.01E+01 NUMERICAL DIFFICULTIES WITH INTEGRATION ROUTINE. MAXIMUM NO. OF EVALUATIONS OF DIFFERENTIAL EQUATIONS, 100000, EXCEEDED. 0PROGRAM TERMINATED BY PRRES Excluding all the additional points, the run is coming to a successfully end using the same MSFI-file. In both cases NONMEM terminates with 0MINIMIZATION TERMINATED DUE TO INABILITY TO PROCEED BEYOND TERMINATION POINT OF PREVIOUS SEARCH NO. OF FUNCTION EVALUATIONS USED: 0 NO. OF SIG. DIGITS IN FINAL EST.: .0 but this is due to the nonchanging SIGDIGITS from the first to the second run, and changing this number is only increasing the CPU-time, which is for the first run about 4 hours (only FO and POSTHOC) !! Did I make some mistakes in including the additionals ?