General Question about the 'Best' Platform for NONMEM
> One more thing. We have found a limit of 400 records under VM on the ESA 9000
> due to the loader not being able to go above 16 meg. Does anyone have any info
> on number of records vs platform?
> One scientist here wants to run a 600 record problem...
probably you have followed the instructions in section III, 2.7 of NONMEM guide III in increasing the maximum number of observation records per individual.
(When you change the default value make sure that when implementing a NONMEM
update the line
PARAMETER (NO= ...)
again is the same in a l l of these files.) Having done this, the size of
NONMEM buffers 1 and 2 (guide III, section III, 2.9) still limits the total
number of records per individual to 400. You may change this limit by modifying
subroutines DAT1 and DAT2. For example, the lines
DIMENSION X(16040)
DATA SIZE/16040/
in file DAT1.f, and
DIMENSION X(2406)
DATA SIZE/2406/
in file DAT2.f allow 800 data records per individual.
I hit this limitation when inserting hundreds of EVID=2 lines in a data set
in order to get smooth prediction curves. When your predictions can be
described by an explicit function (e.g. a sum of exponentials) a better way
of producing smooth predictions may be to extract the parameters of this
function from NONMEM's report file and to have your graphics program produce
the prediction curve.
Response/question from: (gasparini@binfc1.jrf.be) - 22 Nov 1994
There has already been lots of discussions on this channel, regarding
installation of NONMEM on different platforms.
Until now we run NONMEM on VMS (VAX-machine) but we are considering going to
UNIX, for obvious reasons (especially machine precision).
I know that some of you run NONMEM on UNIX and I would like to know more about
your experience on installation on specific machines (Silicon Graphics, SUN,
DEC-ULTIRX....). Are there things to consider before and during installation ?
Our company tends to choose an HP, but this should not be a fixed choice.
Please, kindly reply to GASPARINI@JRF.BE